Recombinant Rabbit Monoclonal Antibodies
The rabbit immune system generates antibody diversity and optimizes affinity by processes that are far more efficient than those of mice and other rodents. In addition, many small molecules and peptides as well as mouse antigens will generate an immune response in rabbits, but will not in mice. Therefore, the rabbit polyclonal antibodies have been widely used in research and diagnostic applications.
BioAtla has developed a robust cloning process for the generation of high-affinity recombinant rabbit monoclonal antibodies in a high throughput manner. The recombinant antibodies offer several advantages over the naturally produced antibodies. The recombinant antibodies will retain and immortalize the specificities of the antibodies, and can be produced in large scale with very low cost. In addition, the recombinant antibodies generated can be further engineered in a multitude of ways to produce antibody variants with higher affinity, altered antigenic specificity, or enhanced stability.
BioAtla is one of the very few companies in the world that offer recombinant rabbit monoclonal antibody production as a service.