We love antibodies.

We make them, we change them, we improve them. Our comprehensive approach to antibody services means a powerful, fast and surprisingly efficient process to accelerate your success. We’re committed to best practices that clients often recognize during the engagement and value even more downstream.

ANTIBODY SERVICES OVERVIEW:

Express Humanization™

to antibody services means a powerful, fast and surprisingly efficient process to accelerate your success. We’re committed to best practices that clients often recognize during the engagement and value even more downstream.
CLICK HERE TO LEARN MORE >

Antibody Affinity Maturation and Functional Engineering

gives you access to comprehensive mutagenesis services to improve antibody characteristics including affinity, specificity, effector function, expression level, stability, and solubility.
CLICK HERE TO LEARN MORE >

Antibody Expression and Purification

using affinity ion exchange chromatography and developed specifically for each antibody following your requirement.

Assay Development and Functional Characterization

using cellular in vitro bioassays and a suite of biochemical assays to measure antibody functions you need like ADCC, CDC, apoptosis, species cross-reactivity and more. Develop your assays using FACS, ELISA, in vivo assays, or other standard and custom methodologies.

Antibody Internalization – New!

using quantitative confocal microscopy study and flow cytometry analysis to evaluate the degree of binding and internationalization of antibody candidates to cells. Immunotoxin potency is dependent on cell surface binding specificity efficiency as well as internalization. CLICK HERE TO LEARN MORE >

Antigen Expression and Purification

including expertise to synthesize, modify and conjugate peptides – all tailored to your specific needs.

Versitope™

leaves unreliable hybridoma-based approaches for discovery of functional antibodies in the dust. Generate thousands of specific antibodies against a target using the power of immunized systems with the combined potential of both natural and combinatorial antibody pairs. Our Versitope™ system will maximize epitope coverage, affinity and functionality, delivering the most cost-effective path to discovery of immunization-induced antibodies. Contact us to learn how we can open up a new universe of antibody epitope coverage for you.

Monoclonal and Polyclonal Antibody Production

based on you exact specifications and with the highest rate of success with rapid turnaround times.

GigaMab™ Fully Human Library

is at your fingertips. A validated full-length IgG library with large numbers of high diversity fully human antibodies expressed in mammalian cells. Ask about our new and expanded, billion-member, mammalian cell-based library.
CLICK HERE TO LEARN MORE >

Class Switch™

is our suite of mammalian expression vectors which allow for easy expression of the same variable domains in the context of different antibody isotypes.CLICK HERE TO LEARN MORE >

Follow-On Biologics

encompass both Biobetter and Biosimilar molecules. Our powerful expression optimization technology for Biosimilar products enables low cost, efficient production. Our suite of engineering technologies also provides best-in-class next generation Biobetter molecules.CLICK HERE TO LEARN MORE >

Ask us about:

  • Our ATLAb™ proprietary antibody engineering and evolution technology platforms for humanization, optimization, production cell line optimization, and assay development
  • Our Humanation™ technology that evolves mouse or other non-human antibodies into fully human antibodies
  • The advantages of our high-affinity recombinant rabbit monoclonal antibodies compared to naturally produced antibodies.
  • How our Multidimensional Epitope Mapping can identify linear, conformational and discontinuous epitopes, resolving the amino acids critical to antibody binding.
  • Expression-optimized Fc domains for improving expression of antibodies in mammalian cells independent of the variable region or mammalian cell line used.

To learn how we can use global resources to right-size a cost-effective solution for you, call us at 858-558-0708 ext. 0 or send us an email.